Pesquisa | Biblioteca Virtual em Saúde

1.

G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.

Prentzell, Mirja Tamara; Rehbein, Ulrike; Cadena Sandoval, Marti; De Meulemeester, Ann-Sofie; Baumeister, Ralf; Brohée, Laura; Berdel, Bianca; Bockwoldt, Mathias; Carroll, Bernadette; Chowdhury, Suvagata Roy; von Deimling, Andreas; Demetriades, Constantinos; Figlia, Gianluca; de Araujo, Mariana Eca Guimaraes; Heberle, Alexander M; Heiland, Ines; Holzwarth, Birgit; Huber, Lukas A; Jaworski, Jacek; Kedra, Magdalena; Kern, Katharina; Kopach, Andrii; Korolchuk, Viktor I; van 't Land-Kuper, Ineke; Macias, Matylda; Nellist, Mark; Palm, Wilhelm; Pusch, Stefan; Ramos Pittol, Jose Miguel; Reil, Michèle; Reintjes, Anja; Reuter, Friederike; Sampson, Julian R; Scheldeman, Chloë; Siekierska, Aleksandra; Stefan, Eduard; Teleman, Aurelio A; Thomas, Laura E; Torres-Quesada, Omar; Trump, Saskia; West, Hannah D; de Witte, Peter; Woltering, Sandra; Yordanov, Teodor E; Zmorzynska, Justyna; Opitz, Christiane A; Thedieck, Kathrin.

Cell ; 184(3): 655-674.e27, 2021 02 04.

Artigo em Inglês | MEDLINE | ID: mdl-33497611

2.

Saltatory Conduction along Myelinated Axons Involves a Periaxonal Nanocircuit.

Cohen, Charles C H; Popovic, Marko A; Klooster, Jan; Weil, Marie-Theres; Möbius, Wiebke; Nave, Klaus-Armin; Kole, Maarten H P.

Cell ; 180(2): 311-322.e15, 2020 01 23.

Artigo em Inglês | MEDLINE | ID: mdl-31883793

3.

Single Residue Variation in Skeletal Muscle Myosin Enables Direct and Selective Drug Targeting for Spasticity and Muscle Stiffness.

Gyimesi, Máté; Horváth, Ádám I; Túrós, Demeter; Suthar, Sharad Kumar; Pénzes, Máté; Kurdi, Csilla; Canon, Louise; Kikuti, Carlos; Ruppel, Kathleen M; Trivedi, Darshan V; Spudich, James A; Lorincz, István; Rauscher, Anna Á; Kovács, Mihály; Pál, Endre; Komoly, Sámuel; Houdusse, Anne; Málnási-Csizmadia, András.

Cell ; 183(2): 335-346.e13, 2020 10 15.

Artigo em Inglês | MEDLINE | ID: mdl-33035452

4.

Development of an Inactivated Vaccine Candidate, BBIBP-CorV, with Potent Protection against SARS-CoV-2.

Wang, Hui; Zhang, Yuntao; Huang, Baoying; Deng, Wei; Quan, Yaru; Wang, Wenling; Xu, Wenbo; Zhao, Yuxiu; Li, Na; Zhang, Jin; Liang, Hongyang; Bao, Linlin; Xu, Yanfeng; Ding, Ling; Zhou, Weimin; Gao, Hong; Liu, Jiangning; Niu, Peihua; Zhao, Li; Zhen, Wei; Fu, Hui; Yu, Shouzhi; Zhang, Zhengli; Xu, Guangxue; Li, Changgui; Lou, Zhiyong; Xu, Miao; Qin, Chuan; Wu, Guizhen; Gao, George Fu; Tan, Wenjie; Yang, Xiaoming.

Cell ; 182(3): 713-721.e9, 2020 08 06.

Artigo em Inglês | MEDLINE | ID: mdl-32778225

5.

Long-Term GABA Administration Induces Alpha Cell-Mediated Beta-like Cell Neogenesis.

Ben-Othman, Nouha; Vieira, Andhira; Courtney, Monica; Record, Fabien; Gjernes, Elisabet; Avolio, Fabio; Hadzic, Biljana; Druelle, Noémie; Napolitano, Tiziana; Navarro-Sanz, Sergi; Silvano, Serena; Al-Hasani, Keith; Pfeifer, Anja; Lacas-Gervais, Sandra; Leuckx, Gunter; Marroquí, Laura; Thévenet, Julien; Madsen, Ole Dragsbaek; Eizirik, Decio Laks; Heimberg, Harry; Kerr-Conte, Julie; Pattou, François; Mansouri, Ahmed; Collombat, Patrick.

Cell ; 168(1-2): 73-85.e11, 2017 Jan 12.

Artigo em Inglês | MEDLINE | ID: mdl-27916274

6.

The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts.

Friscic, Jasna; Böttcher, Martin; Reinwald, Christiane; Bruns, Heiko; Wirth, Benjamin; Popp, Samantha-Josefine; Walker, Kellie Irene; Ackermann, Jochen A; Chen, Xi; Turner, Jason; Zhu, Honglin; Seyler, Lisa; Euler, Maximilien; Kirchner, Philipp; Krüger, René; Ekici, Arif B; Major, Triin; Aust, Oliver; Weidner, Daniela; Fischer, Anita; Andes, Fabian T; Stanojevic, Zeljka; Trajkovic, Vladimir; Herrmann, Martin; Korb-Pap, Adelheid; Wank, Isabel; Hess, Andreas; Winter, Johnathan; Wixler, Viktor; Distler, Jörg; Steiner, Günter; Kiener, Hans P; Frey, Benjamin; Kling, Lasse; Raza, Karim; Frey, Silke; Kleyer, Arnd; Bäuerle, Tobias; Hughes, Timothy R; Grüneboom, Anika; Steffen, Ulrike; Krönke, Gerhard; Croft, Adam P; Filer, Andrew; Köhl, Jörg; Klein, Kerstin; Buckley, Christopher D; Schett, Georg; Mougiakakos, Dimitrios; Hoffmann, Markus H.

Immunity ; 54(5): 1002-1021.e10, 2021 05 11.

Artigo em Inglês | MEDLINE | ID: mdl-33761330

7.

Reconstruction and Simulation of Neocortical Microcircuitry.

Markram, Henry; Muller, Eilif; Ramaswamy, Srikanth; Reimann, Michael W; Abdellah, Marwan; Sanchez, Carlos Aguado; Ailamaki, Anastasia; Alonso-Nanclares, Lidia; Antille, Nicolas; Arsever, Selim; Kahou, Guy Antoine Atenekeng; Berger, Thomas K; Bilgili, Ahmet; Buncic, Nenad; Chalimourda, Athanassia; Chindemi, Giuseppe; Courcol, Jean-Denis; Delalondre, Fabien; Delattre, Vincent; Druckmann, Shaul; Dumusc, Raphael; Dynes, James; Eilemann, Stefan; Gal, Eyal; Gevaert, Michael Emiel; Ghobril, Jean-Pierre; Gidon, Albert; Graham, Joe W; Gupta, Anirudh; Haenel, Valentin; Hay, Etay; Heinis, Thomas; Hernando, Juan B; Hines, Michael; Kanari, Lida; Keller, Daniel; Kenyon, John; Khazen, Georges; Kim, Yihwa; King, James G; Kisvarday, Zoltan; Kumbhar, Pramod; Lasserre, Sébastien; Le Bé, Jean-Vincent; Magalhães, Bruno R C; Merchán-Pérez, Angel; Meystre, Julie; Morrice, Benjamin Roy; Muller, Jeffrey; Muñoz-Céspedes, Alberto.

Cell ; 163(2): 456-92, 2015 Oct 08.

Artigo em Inglês | MEDLINE | ID: mdl-26451489

8.

An O2-sensitive glomus cell-stem cell synapse induces carotid body growth in chronic hypoxia.

Platero-Luengo, Aida; González-Granero, Susana; Durán, Rocío; Díaz-Castro, Blanca; Piruat, José I; García-Verdugo, José Manuel; Pardal, Ricardo; López-Barneo, José.

Cell ; 156(1-2): 291-303, 2014 Jan 16.

Artigo em Inglês | MEDLINE | ID: mdl-24439383

9.

Synaptic and extrasynaptic NMDA receptors are gated by different endogenous coagonists.

Papouin, Thomas; Ladépêche, Laurent; Ruel, Jérôme; Sacchi, Silvia; Labasque, Marilyne; Hanini, Marwa; Groc, Laurent; Pollegioni, Loredano; Mothet, Jean-Pierre; Oliet, Stéphane H R.

Cell ; 150(3): 633-46, 2012 Aug 03.

Artigo em Inglês | MEDLINE | ID: mdl-22863013

10.

Caldendrin and myosin V regulate synaptic spine apparatus localization via ER stabilization in dendritic spines.

Konietzny, Anja; Grendel, Jasper; Kadek, Alan; Bucher, Michael; Han, Yuhao; Hertrich, Nathalie; Dekkers, Dick H W; Demmers, Jeroen A A; Grünewald, Kay; Uetrecht, Charlotte; Mikhaylova, Marina.

EMBO J ; 41(4): e106523, 2022 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-34935159

11.

Na⁺ controls hypoxic signalling by the mitochondrial respiratory chain.

Hernansanz-Agustín, Pablo; Choya-Foces, Carmen; Carregal-Romero, Susana; Ramos, Elena; Oliva, Tamara; Villa-Piña, Tamara; Moreno, Laura; Izquierdo-Álvarez, Alicia; Cabrera-García, J Daniel; Cortés, Ana; Lechuga-Vieco, Ana Victoria; Jadiya, Pooja; Navarro, Elisa; Parada, Esther; Palomino-Antolín, Alejandra; Tello, Daniel; Acín-Pérez, Rebeca; Rodríguez-Aguilera, Juan Carlos; Navas, Plácido; Cogolludo, Ángel; López-Montero, Iván; Martínez-Del-Pozo, Álvaro; Egea, Javier; López, Manuela G; Elrod, John W; Ruíz-Cabello, Jesús; Bogdanova, Anna; Enríquez, José Antonio; Martínez-Ruiz, Antonio.

Nature ; 586(7828): 287-291, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-32728214

12.

Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells.

Kim, Minchul; Wende, Hagen; Walcher, Jan; Kühnemund, Johannes; Cheret, Cyril; Kempa, Stefan; McShane, Erik; Selbach, Matthias; Lewin, Gary R; Birchmeier, Carmen.

Genes Dev ; 32(9-10): 645-657, 2018 05 01.

Artigo em Inglês | MEDLINE | ID: mdl-29748249

13.

Rat hepatocytes secrete free oligosaccharides.

Huang, Chengcheng; Seino, Junichi; Honda, Akinobu; Fujihira, Haruhiko; Wu, Di; Okahara, Kyohei; Kitazume, Shinobu; Nakaya, Shuichi; Kitajima, Ken; Sato, Chihiro; Suzuki, Tadashi.

J Biol Chem ; 300(3): 105712, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38309509

14.

Acetaminophen influences musculoskeletal signaling but not adaptations to endurance exercise training.

Roberts, Brandon M; Geddis, Alyssa V; Ciuciu, Alexandra; Reynoso, Marinaliz; Mehta, Nikhil; Varanoske, Alyssa N; Kelley, Alyssa M; Walker, Raymond J; Munoz, Rigoberto; Kolb, Alexander L; Staab, Jeffery S; Naimo, Marshall A; Tomlinson, Ryan E.

FASEB J ; 38(7): e23586, 2024 Apr 15.

Artigo em Inglês | MEDLINE | ID: mdl-38568858

15.

Ezetimibe ameliorates cisplatin-induced nephrotoxicity: A novel therapeutic approach via modulating AMPK/Nrf2/TXNIP signaling.

Fathy, Nevine; Farouk, Shaimaa; Sayed, Rabab H; Fahim, Atef Tadros.

FASEB J ; 38(1): e23382, 2024 01.

Artigo em Inglês | MEDLINE | ID: mdl-38145344

16.

Reduction in Insulin Uncovers a Novel Effect of VEGFB on Cardiac Substrate Utilization.

Shang, Rui; Lee, Chae Syng; Wang, Hualin; Dyer, Roger; Noll, Christophe; Carpentier, André; Sultan, Ibrahim; Alitalo, Kari; Boushel, Robert; Hussein, Bahira; Rodrigues, Brian.

Arterioscler Thromb Vasc Biol ; 44(1): 177-191, 2024 01.

Artigo em Inglês | MEDLINE | ID: mdl-38150518

17.

Generation of rat pancreas in mouse by interspecific blastocyst injection of pluripotent stem cells.

Kobayashi, Toshihiro; Yamaguchi, Tomoyuki; Hamanaka, Sanae; Kato-Itoh, Megumi; Yamazaki, Yuji; Ibata, Makoto; Sato, Hideyuki; Lee, Youn-Su; Usui, Jo-Ichi; Knisely, A S; Hirabayashi, Masumi; Nakauchi, Hiromitsu.

Cell ; 142(5): 787-99, 2010 Sep 03.

Artigo em Inglês | MEDLINE | ID: mdl-20813264

18.

Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization.

Li, Zheng; Jo, Jihoon; Jia, Jie-Min; Lo, Shih-Ching; Whitcomb, Daniel J; Jiao, Song; Cho, Kwangwook; Sheng, Morgan.

Cell ; 141(5): 859-71, 2010 May 28.

Artigo em Inglês | MEDLINE | ID: mdl-20510932

19.

PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress.

Ranek, Mark J; Kokkonen-Simon, Kristen M; Chen, Anna; Dunkerly-Eyring, Brittany L; Vera, Miguel Pinilla; Oeing, Christian U; Patel, Chirag H; Nakamura, Taishi; Zhu, Guangshuo; Bedja, Djahida; Sasaki, Masayuki; Holewinski, Ronald J; Van Eyk, Jennifer E; Powell, Jonathan D; Lee, Dong Ik; Kass, David A.

Nature ; 566(7743): 264-269, 2019 02.

Artigo em Inglês | MEDLINE | ID: mdl-30700906

20.

Compartmentalized gut lymph node drainage dictates adaptive immune responses.

Esterházy, Daria; Canesso, Maria C C; Mesin, Luka; Muller, Paul A; de Castro, Tiago B R; Lockhart, Ainsley; ElJalby, Mahmoud; Faria, Ana M C; Mucida, Daniel.

Nature ; 569(7754): 126-130, 2019 05.

Artigo em Inglês | MEDLINE | ID: mdl-30988509

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